2 6-dimethylaniline toxicity

TOXICOLOGY AND CARCINOGENESIS OF 2,6=XYLIDINE

2,6-Xylidine - Wikipedia 2,6-Dimethylaniline Revision Date Dec Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. The product contains following substances which are hazardous for the environment. Component Freshwater Algae Freshwater Fish Microtox Water Flea 2,6-Xylidene Not listed LC = mg/L, 96h (Brachydanio.

N,N-Dimethylaniline: C8H11N: CID 949 - PubChem genicity of 2,6-xylidine. The epithelium of the nasal cavity was the primary site affected, both neoplastic and nonneoplastic lesions being ob- served in rats fed diets containing up to 3, ppm 2,g-xylidine for 2 years. Toxic effects were also seen in the liver, kidney, and hematopoietic system.

SAFETY DATA SHEET Revision Date 09/08/2024 Version 6 2,6-Dimethylaniline | C8H11N | CID - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

2,6-Dimethylaniline: C8H11N: CID 6896 - PubChem In male Osborne-Mendel rats given up to 10 ppm 2,6-dimethylaniline in the diet for three to six months, 25% weight retardation, anaemia, liver enlargement (no microscopic change), splenic congestion and kidney damage that included depressed scar formation, tubular atrophy, interstitial fibrosis, chronic inflammation, papillary oedema and.

Safety Data Sheet: 2,6-Dimethylaniline - Carl Roth

These results suggest that rapid and extensive metabolic activation of aniline and its dimethyl derivatives occurred in rats and that the presence of a methyl group at the C 2-positon may generally suppress fast metabolic rates of dimethyl aniline derivatives that promote metabolic activation reactions at NH 2 moieties.

Safety Data Sheet: Fisher Scientific 2,6-Dimethylaniline 2,6-Dimethylaniline sc Hazard Alert Code Key: EXTREME HIGH MODERATE LOW Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION PRODUCT NAME 2,6-Dimethylaniline STATEMENT OF HAZARDOUS NATURE CONSIDERED A HAZARDOUS SUBSTANCE ACCORDING TO OSHA 29 CFR NFPA SUPPLIER Company: Santa Cruz Biotechnology, Inc. Address: Delaware Ave.

TOXICOLOGY AND CARCINOGENESIS OF 2,6=XYLIDINE is a conjugate of 4-hydroxy-2, 6-dimethylaniline. Studies of lidocaine metabolism following intravenous bolus injections have shown that the elimination half-life of this agent is typically to hours. Because of the rapid rate at which lidocaine is metabolized, any condition that affects liver function may alter lidocaine kinetics.

2,6-DIMETHYLANILINE (2,6-XYLIDINE) - Occupational Exposures Acute(short-term) inhalation exposure to N,N-dimethylaniline has resulted in effects on the central nervoussystem (CNS) and circulatory system, with headache, cyanosis, and dizziness in humans. Effects on theblood have been reported in exposed workers.